Gene

TRIM45

Species
Homo sapiens
Symbol
TRIM45
Name
tripartite motif containing 45
Synonyms
  • E3 ubiquitin-protein ligase TRIM45
  • FLJ13181
Biotype
protein coding gene
Automated Description
Enables ubiquitin protein ligase activity. Involved in negative regulation of inflammatory response; proteasome-mediated ubiquitin-dependent protein catabolic process; and protein K48-linked ubiquitination. Located in cytosol; intercellular bridge; and nucleoplasm. Is active in cytoplasm.
RGD Description
Enables ubiquitin protein ligase activity. Involved in negative regulation of inflammatory response; proteasome-mediated ubiquitin-dependent protein catabolic process; and protein K48-linked ubiquitination. Located in cytosol; intercellular bridge; and nucleoplasm. Is active in cytoplasm. [provided by Alliance of Genome Resources, Nov 2024]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR25462
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCh38
Viewer Help
117.112M117.114M117.116M117.118M117.120M117.122M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions