Enables ubiquitin protein ligase activity. Involved in negative regulation of inflammatory response; proteasome-mediated ubiquitin-dependent protein catabolic process; and protein K48-linked ubiquitination. Located in cytosol; intercellular bridge; and nucleoplasm. Is active in cytoplasm.
RGD Description
Enables ubiquitin protein ligase activity. Involved in negative regulation of inflammatory response; proteasome-mediated ubiquitin-dependent protein catabolic process; and protein K48-linked ubiquitination. Located in cytosol; intercellular bridge; and nucleoplasm. Is active in cytoplasm. [provided by Alliance of Genome Resources, Nov 2024]