Gene

ALYREF

Species
Homo sapiens
Symbol
ALYREF
Name
Aly/REF export factor
Synonyms
  • ally of AML-1 and LEF-1
  • ALY
Biotype
protein coding gene
Automated Description
Enables C5-methylcytidine-containing RNA reader activity. Involved in mRNA export from nucleus. Located in chromosome, telomeric region; cytoplasm; and nucleus. Part of catalytic step 2 spliceosome and transcription export complex.
RGD Description
The protein encoded by this gene is a heat stable, nuclear protein and functions as a molecular chaperone. It is thought to regulate dimerization, DNA binding, and transcriptional activity of basic region-leucine zipper (bZIP) proteins. [provided by RefSeq, Jul 2008]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR19965
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCh38
Viewer Help
81.8880M81.8885M81.8890M81.8895M81.8900M81.8905M81.8910M81.8915M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions