activating transcription factor 7 interacting protein
Synonyms
activating transcription factor 7-interacting protein 1
AM
Biotype
protein coding gene
Automated Description
Enables transcription coregulator activity. Involved in DNA methylation-dependent constitutive heterochromatin formation; negative regulation of DNA-templated transcription; and positive regulation of DNA-templated transcription. Located in cytosol and nuclear body.
RGD Description
ATF7IP is a multifunctional nuclear protein that associates with heterochromatin. It can act as a transcriptional coactivator or corepressor depending upon its binding partners (summary by Liu et al., 2009 [PubMed 19106100]).[supplied by OMIM, Nov 2010]