Version: 8.0.0Date: Tue Jan 28 2025
Gene
ZFYVE26
- Species
- Homo sapiens
- Symbol
- ZFYVE26
- Name
- zinc finger FYVE-type containing 26
- Synonyms
- DKFZp686F19106
- DKFZp781H1112
- Biotype
- protein coding gene
- Automated Description
- Enables phosphatidylinositol-3-phosphate binding activity and protein kinase binding activity. Involved in double-strand break repair via homologous recombination and regulation of cytokinesis. Acts upstream of or within autophagosome organization and lysosome organization. Located in several cellular components, including centrosome; endosome; and midbody. Implicated in hereditary spastic paraplegia 15.
- RGD Description
- This gene encodes a protein which contains a FYVE zinc finger binding domain. The presence of this domain is thought to target these proteins to membrane lipids through interaction with phospholipids in the membrane. Mutations in this gene are associated with autosomal recessive spastic paraplegia-15. [provided by RefSeq, Oct 2008]
- Cross References
- Additional Information
- Literature
Orthology
- Gene tree
- PANTHER:PTHR46591
Links to orthology data in JBrowse by filter level: Stringent, Moderate, No filter, Best and Best Reverse
Disease Associations
Cases where the expected disease association was NOT found
Cell color indicative of annotation volume
No data available
Sequence Feature Viewer
- Genome location
- Chr14:67727374...67816590 - (89.22 kb)
- Assembly version
- GRCh38
- Viewer Help
Data currently unavailable; sequence viewer under construction