Version: 8.0.0
Date: Tue Jan 28 2025
SLC15A4
Homo sapiensHGNC:23090
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

SLC15A4

Species
Homo sapiens
Symbol
SLC15A4
Name
solute carrier family 15 member 4
Synonyms
  • FP12591
  • hPHT1
Biotype
protein coding gene
Automated Description
Enables several functions, including L-histidine transmembrane transporter activity; peptide:proton symporter activity; and peptidoglycan transmembrane transporter activity. Involved in dipeptide import across plasma membrane; peptidoglycan transport; and positive regulation of pattern recognition receptor signaling pathway. Located in endolysosome membrane.
RGD Description
Enables several functions, including L-histidine transmembrane transporter activity; peptide:proton symporter activity; and peptidoglycan transmembrane transporter activity. Involved in dipeptide import across plasma membrane; peptidoglycan transport; and positive regulation of pattern recognition receptor signaling pathway. Located in endolysosome membrane. [provided by Alliance of Genome Resources, Nov 2024]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11654
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume
No data available

Alleles and Variants

Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
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    Transgenic Alleles

    No data available

    Models

    Model name
    Experimental condition
    Associated Human Diseases
    Associated Phenotypes
    Modifier
    Source
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      Sequence Feature Viewer

      Genome location
      Assembly version
      GRCh38
      Viewer Help
      Data currently unavailable; sequence viewer under construction

      Sequence Details

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      Expression

      Primary Sources
      None
      Other Sources
      Must provide at least one subject
      Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

      Molecular Interactions

      SLC15A4 molecule type
      Interactor gene
      Interactor species
      Interactor molecule type
      Detection methods
      Source
      Reference
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        Genetic Interactions

        SLC15A4 role
        SLC15A4 genetic perturbation
        Interactor gene
        Interactor species
        Interactor role
        Interactor genetic perturbation
        Interaction type
        Phenotype or trait
        Source
        Reference
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