Gene

HSD17B14

Species
Homo sapiens
Symbol
HSD17B14
Name
hydroxysteroid 17-beta dehydrogenase 14
Synonyms
  • 17-beta-HSD 14
  • 17-beta-hydroxysteroid dehydrogenase 14
Biotype
protein coding gene
Automated Description
Enables estradiol 17-beta-dehydrogenase [NAD(P)+] activity; identical protein binding activity; and testosterone 17-beta-dehydrogenase (NADP+) activity. Involved in steroid catabolic process. Located in cytosol.
RGD Description
17-beta-hydroxysteroid dehydrogenases, such as HSD17B14, are primarily involved in metabolism of steroids at the C17 position and also of other substrates, such as fatty acids, prostaglandins, and xenobiotics (Lukacik et al., 2007 [PubMed 17067289]).[supplied by OMIM, Jun 2009]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR43658
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCh38
Viewer Help
48.814M48.816M48.818M48.820M48.822M48.824M48.826M48.828M48.830M48.832M48.834M48.836M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions