Enables estradiol 17-beta-dehydrogenase [NAD(P)+] activity; identical protein binding activity; and testosterone 17-beta-dehydrogenase (NADP+) activity. Involved in steroid catabolic process. Located in cytosol.
RGD Description
17-beta-hydroxysteroid dehydrogenases, such as HSD17B14, are primarily involved in metabolism of steroids at the C17 position and also of other substrates, such as fatty acids, prostaglandins, and xenobiotics (Lukacik et al., 2007 [PubMed 17067289]).[supplied by OMIM, Jun 2009]