Gene

CRIM1

Species
Homo sapiens
Symbol
CRIM1
Name
cysteine rich transmembrane BMP regulator 1
Synonyms
  • CRIM-1
  • cysteine rich transmembrane BMP regulator 1 (chordin-like)
Biotype
protein coding gene
Automated Description
Enables PDZ domain binding activity. Acts upstream of or within negative regulation of BMP signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane.
RGD Description
This gene encodes a transmembrane protein containing six cysteine-rich repeat domains and an insulin-like growth factor-binding domain. The encoded protein may play a role in tissue development though interactions with members of the transforming growth factor beta family, such as bone morphogenetic proteins. [provided by RefSeq, Nov 2010]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR46439
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCh38
Viewer Help
36.36M36.38M36.40M36.42M36.44M36.46M36.48M36.50M36.52M36.54M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions