Enables PDZ domain binding activity. Acts upstream of or within negative regulation of BMP signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane.
RGD Description
This gene encodes a transmembrane protein containing six cysteine-rich repeat domains and an insulin-like growth factor-binding domain. The encoded protein may play a role in tissue development though interactions with members of the transforming growth factor beta family, such as bone morphogenetic proteins. [provided by RefSeq, Nov 2010]