Gene

AKAP14

Species
Homo sapiens
Symbol
AKAP14
Name
A-kinase anchoring protein 14
Synonyms
  • A kinase (PRKA) anchor protein 14
  • A-kinase anchor protein 14
Biotype
protein coding gene
Automated Description
Enables protein kinase A regulatory subunit binding activity. Located in axoneme. Part of cAMP-dependent protein kinase complex.
RGD Description
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The protein anchors PKA in ciliary axonemes and, in this way, may play a role in regulating ciliary beat frequency. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR35075
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCh38
Viewer Help
119.896M119.898M119.900M119.902M119.904M119.906M119.908M119.910M119.912M119.914M119.916M119.918M119.920M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions