Version: 8.0.0Date: Tue Jan 28 2025
Gene
INTS7
- Species
- Homo sapiens
- Symbol
- INTS7
- Name
- integrator complex subunit 7
- Synonyms
- C1orf73
- DKFZp434B168
- Biotype
- protein coding gene
- Automated Description
- Involved in DNA damage checkpoint signaling; cellular response to ionizing radiation; and snRNA processing. Located in chromosome; cytoplasm; and nuclear body. Part of integrator complex. Is active in nucleus.
- RGD Description
- This gene encodes a subunit of the integrator complex. The integrator complex associates with the C-terminal domain of RNA polymerase II and mediates 3'-end processing of the small nuclear RNAs U1 and U2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
- Cross References
- Additional Information
- Literature
Orthology
- Gene tree
- PANTHER:PTHR13322
Links to orthology data in JBrowse by filter level: Stringent, Moderate, No filter, Best and Best Reverse
Disease Associations
Cases where the expected disease association was NOT found
Cell color indicative of annotation volume
Gene | Association | Disease Qualifier | Disease | Evidence | Source | Based On | References |
|---|---|---|---|---|---|---|---|
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Sequence Feature Viewer
- Genome location
- Chr1:211940399...212035557 - (95.16 kb)
- Assembly version
- GRCh38
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