Gene

LSM14A

Species
Homo sapiens
Symbol
LSM14A
Name
LSM14A mRNA processing body assembly factor
Synonyms
  • alphaSNBP
  • C19orf13
Biotype
protein coding gene
Automated Description
Enables RNA binding activity. Involved in P-body assembly; mitotic spindle assembly; and negative regulation of translation. Located in cytoplasmic ribonucleoprotein granule; cytosol; and mitotic spindle.
RGD Description
Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.[supplied by OMIM, Mar 2008]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR13586
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCh38
Viewer Help
34.18M34.19M34.20M34.21M34.22M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions