Version: 8.0.0
Date: Tue Jan 28 2025
PRAMEF20
Homo sapiensHGNC:25224
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

PRAMEF20

Species
Homo sapiens
Symbol
PRAMEF20
Name
PRAME family member 20
Synonyms
  • PRAME family member 20/21
  • PRAME family member 21
Biotype
protein coding gene
Automated Description
Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be part of Cul2-RING ubiquitin ligase complex. Predicted to be active in cytoplasm.
RGD Description
Predicted to be involved in several processes, including negative regulation of DNA-templated transcription; negative regulation of apoptotic process; and positive regulation of cell population proliferation. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Nov 2024]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR14224
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
PRAMEF25147688827 of 8☑ ☑☐☑☑☑☑☑ 
PRAMEF26147688827 of 8☑ ☑☐☑☑☑☑☑ 
PRAMEF6247688827 of 8☑ ☑☐☑☑☑☑☑ 
PRAMEF15347688827 of 8☑ ☑☐☑☑☑☑☑ 
PRAMEF5447688827 of 8☑ ☑☐☑☑☑☑☑ 
PRAMEF4547687817 of 8☑ ☑☐☑☑☑☑☑ 
PRAMEF11647687817 of 8☑ ☑☐☑☑☑☑☑ 
PRAMEF27747687807 of 8☑ ☑☐☑☑☑☑☑ 
PRAMEF9847687816 of 8☑ ☑☐☑☑☐☑☑ 
PRAMEF12948074637 of 8☑ ☑☐☑☑☑☑☑ 
PRAMEF81047675627 of 8☑ ☑☐☑☑☑☑☑ 
PRAMEF71147675627 of 8☑ ☑☐☑☑☑☑☑ 
PRAME1250163507 of 8☑ ☑☐☑☑☑☑☑ 
PRAMEF181347567546 of 8☑ ☑☐☑☐☑☑☑ 
PRAMEF191447466546 of 8☑ ☑☐☑☐☑☑☑ 
PRAMEF221547567545 of 8☐ ☑☐☑☐☑☑☑ 
PRAMEF11647564516 of 8☑ ☑☐☑☐☑☑☑ 
PRAMEF101746265516 of 8☑ ☑☐☑☐☑☑☑ 
PRAMEF331846265515 of 8☑ ☐☐☑☐☑☑☑ 
PRAMEF171946565534 of 8☑ ☐☐☑☐☑☑☐ 
PRAMEF142047564514 of 8☑ ☐☐☑☐☑☑☐ 
PRAMEF132147563504 of 8☑ ☐☐☑☐☑☑☐ 
PRAMEF22247562504 of 8☑ ☐☐☑☐☑☑☐ 
LRRC142350647303 of 8☑ ☐☐☐☐☑☑☐ 
LRRC14B2445342263 of 8☑ ☐☐☐☐☑☑☐ 

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume
No data available

Alleles and Variants

Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
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    Transgenic Alleles

    No data available

    Models

    No data available

    Sequence Feature Viewer

    Genome location
    Assembly version
    GRCh38
    Viewer Help
    Data currently unavailable; sequence viewer under construction

    Sequence Details

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    Expression

    Primary Sources
    None
    Other Sources
    Must provide at least one subject
    Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

    Molecular Interactions

    1 interactor gene based on 1 annotation
    PRAMEF20 molecule type
    Interactor gene
    Interactor species
    Interactor molecule type
    Detection methods
    Source
    Reference
    protein
    		CUL3Homo sapiens
    protein
    • affinity chromatography technology
    		PMID:37788672
    Showing 1 - 1 of 1 rows
    per page

    Genetic Interactions

    No data available