Gene

CMPK2

Species
Homo sapiens
Symbol
CMPK2
Name
cytidine/uridine monophosphate kinase 2
Synonyms
  • cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
  • cytidylate kinase 2
Biotype
protein coding gene
Automated Description
Enables (d)CMP kinase activity; UMP kinase activity; and nucleoside diphosphate kinase activity. Predicted to be involved in dTDP biosynthetic process; dTTP biosynthetic process; and dUDP biosynthetic process. Predicted to act upstream of or within cellular response to lipopolysaccharide. Located in mitochondrion and nucleoplasm. Biomarker of multiple sclerosis.
RGD Description
This gene encodes one of the enzymes in the nucleotide synthesis salvage pathway that may participate in terminal differentiation of monocytic cells. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10344
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCh38
Viewer Help
6.845M6.850M6.855M6.860M6.865M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions