Enables (d)CMP kinase activity; UMP kinase activity; and nucleoside diphosphate kinase activity. Predicted to be involved in dTDP biosynthetic process; dTTP biosynthetic process; and dUDP biosynthetic process. Predicted to act upstream of or within cellular response to lipopolysaccharide. Located in mitochondrion and nucleoplasm. Biomarker of multiple sclerosis.
RGD Description
This gene encodes one of the enzymes in the nucleotide synthesis salvage pathway that may participate in terminal differentiation of monocytic cells. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]