Gene

AMZ2

Species
Homo sapiens
Symbol
AMZ2
Name
archaelysin family metallopeptidase 2
Synonyms
  • archaemetzincin-2
  • archaemetzincins-2
Biotype
protein coding gene
Automated Description
Predicted to enable metal ion binding activity and metallopeptidase activity. Predicted to be involved in proteolysis.
RGD Description
The protein encoded by this gene is a zinc metalloprotease that displays some activity against angiotensin-3. The encoded protein is inhibited by the aminopeptidase inhibitor amastatin, as well as by the general inhibitors o-phenanthroline and batimastat. Defects in this gene may be associated with lung tumorigenesis. [provided by RefSeq, Oct 2016]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR32205
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCh38
Viewer Help
68.210M68.215M68.220M68.225M68.230M68.235M68.240M68.245M68.250M68.255M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions