Involved in mitotic cytokinetic process; mitotic nuclear division; and nuclear chromosome segregation. Located in several cellular components, including cellularization cleavage furrow; intercellular bridge; and midbody. Implicated in Hodgkin's lymphoma.
RGD Description
This gene encodes a protein which forms a distinct beta-propeller protein structure of kelch domains allowing for protein-protein interactions. Mutations in this gene have been associated with Hodgkin lymphoma. [provided by RefSeq, Sep 2010]