Gene

KLHDC8B

Species
Homo sapiens
Symbol
KLHDC8B
Name
kelch domain containing 8B
Synonyms
  • CHL
  • FLJ11302
Biotype
protein coding gene
Automated Description
Involved in mitotic cytokinetic process; mitotic nuclear division; and nuclear chromosome segregation. Located in several cellular components, including cellularization cleavage furrow; intercellular bridge; and midbody. Implicated in Hodgkin's lymphoma.
RGD Description
This gene encodes a protein which forms a distinct beta-propeller protein structure of kelch domains allowing for protein-protein interactions. Mutations in this gene have been associated with Hodgkin lymphoma. [provided by RefSeq, Sep 2010]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR46260
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCh38
Viewer Help
49.1720M49.1725M49.1730M49.1735M49.1740M49.1745M49.1750M49.1755M49.1760M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions