Gene

DMC1

Species
Homo sapiens
Symbol
DMC1
Name
DNA meiotic recombinase 1
Synonyms
  • disrupted meiotic cDNA1, yeast, homolog of
  • dJ199H16.1
Biotype
protein coding gene
Automated Description
Enables ATP-dependent activity, acting on DNA and identical protein binding activity. Involved in reciprocal meiotic recombination. Located in nucleus.
RGD Description
This gene encodes a member of the superfamily of recombinases (also called DNA strand-exchange proteins). Recombinases are important for repairing double-strand DNA breaks during mitosis and meiosis. This protein, which is evolutionarily conserved, is reported to be essential for meiotic homologous recombination and may thus play an important role in generating diversity of genetic information. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR22942
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCh38
Viewer Help
38.51M38.52M38.53M38.54M38.55M38.56M38.57M

Sequence Details

Loading...

Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions