Gene

SPIC

Species
Homo sapiens
Symbol
SPIC
Name
Spi-C transcription factor
Synonyms
  • MGC40611
  • SPI-C
Biotype
protein coding gene
Automated Description
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within blastocyst development and positive regulation of transcription by RNA polymerase II. Predicted to be located in chromatin. Predicted to be active in nucleus.
RGD Description
The protein encoded by this gene regulates the development of red pulp macrophages, which are necessary for iron homeostasis and the recycling of red blood cells. [provided by RefSeq, Aug 2016]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11849
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Transgenic Alleles

No data available

Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
GRCh38
Viewer Help
101.476M101.478M101.480M101.482M101.484M101.486M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

9 interactor genes based on 13 annotations
SPIC molecule type
Interactor gene
Interactor species
Interactor molecule type
Detection methods
Source
Reference
protein
APPHomo sapiens
protein
  • pull down
PMID:21832049
protein
CCL23Homo sapiens
gene
  • one hybrid
PMID:33179750
protein
CCL23Homo sapiens
gene
  • one hybrid
PMID:33179750
protein
CCL24Homo sapiens
gene
  • one hybrid
PMID:33179750
protein
CCL24Homo sapiens
gene
  • one hybrid
PMID:33179750
protein
IFNA2Homo sapiens
gene
  • one hybrid
PMID:33179750
protein
IFNA2Homo sapiens
gene
  • one hybrid
PMID:33179750
protein
IL18Homo sapiens
gene
  • one hybrid
PMID:33179750
protein
IL18Homo sapiens
gene
  • one hybrid
PMID:33179750
protein
INTS11Homo sapiens
protein
  • two hybrid
PMID:32296183
Showing 1 - 10 of 13 rows
per page

Genetic Interactions