Gene

SYNPO

Species
Homo sapiens
Symbol
SYNPO
Name
synaptopodin
Synonyms
  • KIAA1029
  • SYNPO1
Biotype
protein coding gene
Automated Description
Predicted to enable actin binding activity. Predicted to be involved in several processes, including modification of dendritic spine; modulation of chemical synaptic transmission; and regulation of actin filament bundle assembly. Located in actin cytoskeleton; cytosol; and plasma membrane. Biomarker of chronic kidney disease.
RGD Description
Synaptopodin is an actin-associated protein that may play a role in actin-based cell shape and motility. The name synaptopodin derives from the protein's associations with postsynaptic densities and dendritic spines and with renal podocytes (Mundel et al., 1997 [PubMed 9314539]).[supplied by OMIM, Mar 2008]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24217
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCh38
Viewer Help
150.59M150.60M150.61M150.62M150.63M150.64M150.65M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions