Predicted to enable actin binding activity. Predicted to be involved in several processes, including modification of dendritic spine; modulation of chemical synaptic transmission; and regulation of actin filament bundle assembly. Located in actin cytoskeleton; cytosol; and plasma membrane. Biomarker of chronic kidney disease.
RGD Description
Synaptopodin is an actin-associated protein that may play a role in actin-based cell shape and motility. The name synaptopodin derives from the protein's associations with postsynaptic densities and dendritic spines and with renal podocytes (Mundel et al., 1997 [PubMed 9314539]).[supplied by OMIM, Mar 2008]