Gene

DGKK

Species
Homo sapiens
Symbol
DGKK
Name
diacylglycerol kinase kappa
Synonyms
  • 142 kDa diacylglycerol kinase
  • DAG kinase kappa
Biotype
protein coding gene
Automated Description
Enables ATP-dependent diacylglycerol kinase activity. Involved in diacylglycerol metabolic process; intracellular signal transduction; and response to oxidative stress. Located in plasma membrane.
RGD Description
The protein encoded by this gene is an enzyme that phosphorylates diacylglycerol, converting it to phosphatidic acid. The encoded protein is a membrane protein and is inhibited by hydrogen peroxide. Variations in this gene have been associated with hypospadias. [provided by RefSeq, Mar 2011]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11255
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCh38
Viewer Help
50.37M50.38M50.39M50.40M50.41M50.42M50.43M50.44M50.45M50.46M50.47M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions