Gene

ZGLP1

Species
Homo sapiens
Symbol
ZGLP1
Name
zinc finger GATA like protein 1
Synonyms
  • FLJ39511
  • FLJ39703
Biotype
protein coding gene
Automated Description
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in oocyte development; regulation of transcription by RNA polymerase II; and spermatogenesis. Predicted to be located in nucleoplasm. Predicted to be active in nucleus.
RGD Description
ZGLP1 encodes an evolutionary conserved transcriptional regulator with GATA-like zinc fingers. In females, it is expressed in embryonic germ cells and is essential for oogenic fate determination. It acts downstream of bone morphogenetic protein (BMP) and is involved in the regulation of genes involved in RNA processing, transcription and chromatin modification, retrotransposon regulation, meiotic cell cycle, and oocyte development. In males it is not required for the germ cell sex determination but is required by the spermatogonia for efficiently completing the meiotic prophase. [provided by RefSeq, Jul 2022]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR47341
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Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
Phenotype Term
Annotation details
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    Disease Associations

    Cases where the expected disease association was NOT found
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    Alleles and Variants

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      Transgenic Alleles

      Species
      (carrying the transgene)
      Allele symbol
      Transgenic construct
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        Models

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          Sequence Feature Viewer

          Genome location
          Assembly version
          GRCh38
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          Sequence Details

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          Expression

          Primary Sources
          None
          Other Sources
          Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

          Molecular Interactions

          ZGLP1 molecule type
          Interactor gene
          Interactor species
          Interactor molecule type
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            Genetic Interactions

            ZGLP1 role
            ZGLP1 genetic perturbation
            Interactor gene
            Interactor species
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            Interactor genetic perturbation
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            Phenotype or trait
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