fibronectin-like domain-containing leucine-rich transmembrane protein 1
leucine-rich repeat transmembrane protein FLRT1
Biotype
protein coding gene
Automated Description
Predicted to enable fibroblast growth factor receptor binding activity. Predicted to be involved in dendrite development; fibroblast growth factor receptor signaling pathway; and neuron projection extension. Predicted to act upstream of or within positive regulation of synapse assembly. Predicted to be located in several cellular components, including focal adhesion; neuronal cell body membrane; and perinuclear region of cytoplasm. Predicted to be active in extracellular space.
RGD Description
This gene encodes a member of the fibronectin leucine rich transmembrane protein (FLRT) family. The family members may function in cell adhesion and/or receptor signalling. Their protein structures resemble small leucine-rich proteoglycans found in the extracellular matrix. The encoded protein shares sequence similarity with two other family members, FLRT2 and FLRT3. This gene is expressed in kidney and brain. [provided by RefSeq, Jul 2008]