Gene

FLRT1

Species
Homo sapiens
Symbol
FLRT1
Name
fibronectin leucine rich transmembrane protein 1
Synonyms
  • fibronectin-like domain-containing leucine-rich transmembrane protein 1
  • leucine-rich repeat transmembrane protein FLRT1
Biotype
protein coding gene
Automated Description
Predicted to enable fibroblast growth factor receptor binding activity. Predicted to be involved in dendrite development; fibroblast growth factor receptor signaling pathway; and neuron projection extension. Predicted to act upstream of or within positive regulation of synapse assembly. Predicted to be located in several cellular components, including focal adhesion; neuronal cell body membrane; and perinuclear region of cytoplasm. Predicted to be active in extracellular space.
RGD Description
This gene encodes a member of the fibronectin leucine rich transmembrane protein (FLRT) family. The family members may function in cell adhesion and/or receptor signalling. Their protein structures resemble small leucine-rich proteoglycans found in the extracellular matrix. The encoded protein shares sequence similarity with two other family members, FLRT2 and FLRT3. This gene is expressed in kidney and brain. [provided by RefSeq, Jul 2008]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR45712
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCh38
Viewer Help
64.04M64.05M64.06M64.07M64.08M64.09M64.10M64.11M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions