Gene

GABRA6

Species
Homo sapiens
Symbol
GABRA6
Name
gamma-aminobutyric acid type A receptor subunit alpha6
Synonyms
  • GABA subunit A receptor alpha 6
  • GABA(A) receptor subunit alpha-6
Biotype
protein coding gene
Automated Description
Predicted to enable GABA-gated chloride ion channel activity. Predicted to contribute to GABA-A receptor activity; benzodiazepine receptor activity; and chloride channel activity. Predicted to be involved in several processes, including GABAergic synaptic transmission; chloride transmembrane transport; and inhibitory synapse assembly. Predicted to be located in postsynaptic specialization membrane. Predicted to be part of GABA-A receptor complex and transmembrane transporter complex. Predicted to be active in several cellular components, including cerebellar Golgi cell to granule cell synapse; dendrite membrane; and hippocampal mossy fiber to CA3 synapse.
RGD Description
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. [provided by RefSeq, Jul 2008]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR18945
No data available
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Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

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None
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    Disease Associations

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      Alleles and Variants

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        Transgenic Alleles

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        (carrying the transgene)
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          Models

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            Sequence Feature Viewer

            Genome location
            Assembly version
            GRCh38
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            161.56M161.58M161.60M161.62M161.64M161.66M161.68M161.70M

            Sequence Details

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            Expression

            Primary Sources
            None
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            GABRA6 molecule type
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              Genetic Interactions

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