Gene

NCR3LG1

Species
Homo sapiens
Symbol
NCR3LG1
Name
natural killer cell cytotoxicity receptor 3 ligand 1
Synonyms
  • B7 homolog 6
  • B7-H6
Biotype
protein coding gene
Automated Description
Enables receptor ligand activity. Involved in NK T cell activation. Is active in plasma membrane.
RGD Description
B7H6 belongs to the B7 family (see MIM 605402) and is selectively expressed on tumor cells. Interaction of B7H6 with NKp30 (NCR3; MIM 611550) results in natural killer (NK) cell activation and cytotoxicity (Brandt et al., 2009 [PubMed 19528259]).[supplied by OMIM, Jan 2011]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR23411
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCh38
Viewer Help
17.355M17.360M17.365M17.370M17.375M17.380M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions