Version: 8.0.0
Date: Tue Jan 28 2025
USP17L21
Homo sapiensHGNC:44449
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

USP17L21

Species
Homo sapiens
Symbol
USP17L21
Name
ubiquitin specific peptidase 17 like family member 21
Synonyms
  • ubiquitin carboxyl-terminal hydrolase 17-like protein 21
  • ubiquitin specific peptidase 17-like family member 21
Biotype
protein coding gene
Automated Description
Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in regulation of apoptotic process and regulation of protein stability. Predicted to be located in endoplasmic reticulum. Predicted to be active in cytosol and nucleus.
RGD Description
Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in protein deubiquitination and regulation of apoptotic process. Predicted to be located in endoplasmic reticulum. Predicted to be active in cytosol and nucleus. [provided by Alliance of Genome Resources, Nov 2024]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24006
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Must provide at least one subject
    Cell color indicative of annotation volume
    No data available

    Alleles and Variants

    Allele/Variant Symbol
    Allele Synonyms
    Category
    Variant
    Variant type
    Molecular consequence
    Has Disease Annotations
    Has Phenotype Annotations
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      Transgenic Alleles

      Species
      (carrying the transgene)
      Allele symbol
      Transgenic construct
      Expressed components
      Knock-down targets
      Regulatory regions
      Has Disease Annotations
      Has Phenotype Annotations
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        Models

        No data available

        Sequence Feature Viewer

        Genome location
        Assembly version
        GRCh38
        Viewer Help
        Data currently unavailable; sequence viewer under construction

        Sequence Details

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        Expression

        Primary Sources
        None
        Other Sources
        Must provide at least one subject
        Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

        Molecular Interactions

        USP17L21 molecule type
        Interactor gene
        Interactor species
        Interactor molecule type
        Detection methods
        Source
        Reference
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          Genetic Interactions

          USP17L21 role
          USP17L21 genetic perturbation
          Interactor gene
          Interactor species
          Interactor role
          Interactor genetic perturbation
          Interaction type
          Phenotype or trait
          Source
          Reference
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