Species | Gene symbol | Count | Best | Best reverse | Method Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN |
---|---|---|---|---|---|
Mus musculus | H3f3b | 9 of 10 | Yes | Yes | ☐☑☑☑☑☑☑☑☑☑ |
Mus musculus | H3f3a | 9 of 10 | Yes | Yes | ☐☑☑☑☑☑☑☑☑☑ |
Rattus norvegicus | H3f3a | 9 of 10 | Yes | Yes | ☐☑☑☑☑☑☑☑☑☑ |
Xenopus tropicalis | h3-3a | 8 of 9 | Yes | Yes | ☐ ☑☑☑☑☑☑☑☑ |
Xenopus tropicalis | h3-3b | 8 of 9 | Yes | Yes | ☐ ☑☑☑☑☑☑☑☑ |
Xenopus tropicalis | h3c13 | 2 of 9 | Yes | Yes | ☐ ☐☐☑☑☐☐☐☐ |
Danio rerio | h3f3a | 9 of 10 | Yes | Yes | ☐ ☑☑☑☑☑☑☑☑ ☑ |
Danio rerio | h3f3d | 8 of 10 | No | Yes | ☐ ☑☑☑☑☑☑☑☑ ☐ |
Danio rerio | si:ch1073-429i10.3 | 8 of 10 | No | Yes | ☐ ☑☑☑☑☑☑☑☑ ☐ |
Danio rerio | h3f3b.1 | 8 of 10 | No | Yes | ☐ ☑☑☑☑☑☑☑☑ ☐ |
Danio rerio | h3f3c | 8 of 10 | No | Yes | ☐ ☑☑☑☑☑☑☑☑ ☐ |
Drosophila melanogaster | His3.3B | 8 of 9 | Yes | Yes | ☐ ☑☑☑☑☑☑☑☑ |
Drosophila melanogaster | His3.3A | 8 of 9 | Yes | Yes | ☐ ☑☑☑☑☑☑☑☑ |
Caenorhabditis elegans | his-71 | 7 of 9 | Yes | Yes | ☐ ☑☑☑☑☑☑☐☑ |
Caenorhabditis elegans | his-72 | 4 of 9 | No | Yes | ☐ ☐☐☑☑☑☑☐☐ |
Saccharomyces cerevisiae | HHT1 | 6 of 9 | Yes | Yes | ☐ ☐☑☑☑☑☑☐☑ |
Saccharomyces cerevisiae | HHT2 | 6 of 9 | Yes | Yes | ☐ ☐☑☑☑☑☑☐☑ |
Gene symbol | Rank | Alignment Length (aa) | Similarity % | Identity % | Method Count | Method Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD |
---|---|---|---|---|---|---|
H3C14 | 1 | 136 | 99 | 97 | 8 of 8 | ☑ ☑☑☑☑☑☑☑ |
H3C1 | 2 | 136 | 99 | 96 | 8 of 8 | ☑ ☑☑☑☑☑☑☑ |
H3-7 | 3 | 136 | 97 | 94 | 8 of 8 | ☑ ☑☑☑☑☑☑☑ |
H3-4 | 4 | 136 | 97 | 93 | 8 of 8 | ☑ ☑☑☑☑☑☑☑ |
H3-5 | 5 | 136 | 96 | 96 | 7 of 8 | ☑ ☑☐☑☑☑☑☑ |
H3Y2 | 6 | 136 | 91 | 82 | 3 of 8 | ☑ ☐☐☐☐☑☑☐ |
H3Y1 | 7 | 134 | 91 | 82 | 3 of 8 | ☑ ☐☐☐☐☑☑☐ |
CENPA | 8 | 132 | 63 | 52 | 3 of 8 | ☑ ☐☐☐☐☑☑☐ |
Phenotype Term | Annotation details | References |
---|---|---|
Agenesis of corpus callosum | ||
Anteverted nares | ||
Atrial septal defect | ||
Autistic behavior | ||
Autosomal dominant inheritance | ||
Bicuspid aortic valve | ||
Broad philtrum | ||
Broad thumb | ||
Cerebellar vermis hypoplasia | ||
Cerebral cortical atrophy |
Allele/Variant Symbol | Allele Synonyms | Category | Variant | Variant type | Molecular consequence | Has Disease Annotations | Has Phenotype Annotations |
---|---|---|---|---|---|---|---|
NC_000001.11:g.226071445A>G | variant | SNP
| |||||
NC_000001.11:g.226064434A>T | variant | SNP
| |||||
NC_000001.11:g.226064438T>G | variant | SNP
| |||||
NC_000001.11:g.226071376G>A | variant | SNP
| |||||
NC_000001.11:g.226064371C>G | variant | SNP
| |||||
NC_000001.11:g.226065676G>A | variant | SNP
| |||||
NC_000001.11:g.226065777C>G | variant | SNP
| |||||
NC_000001.11:g.226071348C>T | variant | SNP
| |||||
NC_000001.11:g.226064429T>C | variant | SNP
| |||||
NC_000001.11:g.226071394A>G | variant | SNP
|
Species (carrying the transgene) | Allele symbol | Transgenic construct | Expressed components | Knock-down targets | Regulatory regions | Has Disease Annotations | Has Phenotype Annotations |
---|---|---|---|---|---|---|---|
Drosophila melanogaster | Hsap\H3-3AK27M.UAS.Tag:FLAG,Tag:HA |
|
| Yes | |||
Drosophila melanogaster | Hsap\H3-3AK27M.UAS.Tag:FLAG |
|
| ||||
Drosophila melanogaster | Hsap\H3-3AK27M.UAS.Tag:HA |
|
| ||||
Drosophila melanogaster | Hsap\H3-3AK27R.UAS.Tag:FLAG |
|
| ||||
Drosophila melanogaster | Hsap\H3-3AK36M.UAS.Tag:FLAG,Tag:HA |
|
| ||||
Drosophila melanogaster | Hsap\H3-3AK4A.UAS.Tag:FLAG,Tag:HA |
|
| ||||
Drosophila melanogaster | Hsap\H3-3AK4M.UAS.Tag:FLAG,Tag:HA |
|
| ||||
Drosophila melanogaster | Hsap\H3-3AK4M.UASp.Tag:FLAG,Tag:HA |
|
| ||||
Drosophila melanogaster | Hsap\H3-3AK79M.UAS.Tag:FLAG,Tag:HA |
|
| ||||
Drosophila melanogaster | Hsap\H3-3AK9M.UAS.Tag:FLAG,Tag:HA |
|
|
H3-3A molecule type | Interactor gene | Interactor species | Interactor molecule type | Detection methods | Source | Reference |
---|---|---|---|---|---|---|
protein | ABRAXAS1 | Homo sapiens | protein |
| PMID:36089195 | |
protein | ACTG1 | Homo sapiens | protein |
| PMID:23160995 | |
protein | ACTL6A | Homo sapiens | protein |
| PMID:36089195 | |
protein | ADNP | Homo sapiens | protein |
| PMID:36089195 | |
protein | ADNP2 | Homo sapiens | protein |
| PMID:36089195 | |
protein | AFF4 | Homo sapiens | protein |
| PMID:36089195 | |
protein | AHCTF1 | Homo sapiens | protein |
| PMID:36089195 | |
protein | ANAPC7 | Homo sapiens | protein |
| PMID:36089195 | |
protein | ANLN | Homo sapiens | protein |
| PMID:36089195 | |
protein | AP4M1 | Homo sapiens | protein |
| PMID:26496610 |
H3-3A role | H3-3A genetic perturbation | Interactor gene | Interactor species | Interactor role | Interactor genetic perturbation | Interaction type | Phenotype or trait | Source | Reference |
---|---|---|---|---|---|---|---|---|---|
unspecified role | EGFR | Homo sapiens | unspecified role | negative genetic interaction (sensu BioGRID) |
| PMID:34373451 | |||
unspecified role | KRAS | Homo sapiens | unspecified role | negative genetic interaction (sensu BioGRID) |
| PMID:34373451 | |||
unspecified role | RIT1 | Homo sapiens | unspecified role | negative genetic interaction (sensu BioGRID) |
| PMID:34373451 |