Gene

INPP5A

Species
Homo sapiens
Symbol
INPP5A
Name
inositol polyphosphate-5-phosphatase A
Synonyms
  • 43 kDa inositol polyphosphate 5-phophatase
  • 43 kDa inositol polyphosphate 5-phosphatase
Biotype
protein coding gene
Automated Description
Enables PH domain binding activity and inositol-polyphosphate 5-phosphatase activity. Predicted to be involved in negative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway. Located in plasma membrane.
RGD Description
The protein encoded by this gene is a membrane-associated type I inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation. [provided by RefSeq, Jul 2008]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR12997
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCh38
Viewer Help
132.54M132.56M132.58M132.60M132.62M132.64M132.66M132.68M132.70M132.72M132.74M132.76M132.78M

Sequence Details

Loading...

Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions