Enables PH domain binding activity and inositol-polyphosphate 5-phosphatase activity. Predicted to be involved in negative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway. Located in plasma membrane.
RGD Description
The protein encoded by this gene is a membrane-associated type I inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation. [provided by RefSeq, Jul 2008]