potassium two pore domain channel subfamily K member 6
Synonyms
FLJ12282
inward rectifying potassium channel protein TWIK-2
Biotype
protein coding gene
Automated Description
Enables potassium channel activity. Predicted to be involved in positive regulation of NLRP3 inflammasome complex assembly; potassium ion transmembrane transport; and regulation of lysosome size. Predicted to act upstream of or within negative regulation of systemic arterial blood pressure and regulation of resting membrane potential. Located in lysosomal membrane.
RGD Description
This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. This channel protein, considered an open rectifier, is widely expressed. It is stimulated by arachidonic acid, and inhibited by internal acidification and volatile anaesthetics. [provided by RefSeq, Jul 2008]