Gene

MAPK13

Species
Homo sapiens
Symbol
MAPK13
Name
mitogen-activated protein kinase 13
Synonyms
  • MAP kinase 13
  • MAP kinase p38 delta
Biotype
protein coding gene
Automated Description
Enables MAP kinase activity. Involved in several processes, including cellular response to anisomycin; cellular response to sodium arsenite; and cellular response to sorbitol. Predicted to be located in cytosol. Predicted to be active in cytoplasm and nucleus.
RGD Description
This gene encodes a member of the mitogen-activated protein (MAP) kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The encoded protein is a p38 MAP kinase and is activated by proinflammatory cytokines and cellular stress. Substrates of the encoded protein include the transcription factor ATF2 and the microtubule dynamics regulator stathmin. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24055
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCh38
Viewer Help
36.128M36.130M36.132M36.134M36.136M36.138M36.140M36.142M36.144M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions