Predicted to be involved in neuron cell-cell adhesion and neuron migration. Predicted to act upstream of or within cell migration; cell-cell adhesion; and locomotory behavior. Predicted to be located in clathrin-coated vesicle; external side of plasma membrane; and perikaryon. Predicted to be active in endosome and membrane.
RGD Description
Astrotactin is a neuronal adhesion molecule required for glial-guided migration of young postmitotic neuroblasts in cortical regions of developing brain, including cerebrum, hippocampus, cerebellum, and olfactory bulb (Fink et al., 1995).[supplied by OMIM, Jun 2009]