Gene

NR5A2

Species
Homo sapiens
Symbol
NR5A2
Name
nuclear receptor subfamily 5 group A member 2
Synonyms
  • alpha-1-fetoprotein transcription factor
  • b1-binding factor, hepatocyte transcription factor which activates enhancer II of hepatitis B virus
Biotype
protein coding gene
Automated Description
Enables several functions, including nuclear receptor activity; transcription cis-regulatory region binding activity; and transcription coregulator binding activity. Involved in positive regulation of transcription by RNA polymerase II and positive regulation of viral genome replication. Located in cytoplasm and nucleus. Biomarker of colon cancer.
RGD Description
The protein encoded by this gene is a DNA-binding zinc finger transcription factor and is a member of the fushi tarazu factor-1 subfamily of orphan nuclear receptors. The encoded protein is involved in the expression of genes for hepatitis B virus and cholesterol biosynthesis, and may be an important regulator of embryonic development. [provided by RefSeq, Jun 2016]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24086
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCh38
Viewer Help
200.04M200.06M200.08M200.10M200.12M200.14M200.16M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions