Enables G protein-coupled neurotensin receptor activity and identical protein binding activity. Involved in negative regulation of apoptotic process and neuropeptide signaling pathway. Located in membrane raft and plasma membrane. Implicated in schizophrenia. Biomarker of Parkinson's disease.
RGD Description
Neurotensin receptor 1 belongs to the large superfamily of G-protein coupled receptors. NTSR1 mediates the multiple functions of neurotensin, such as hypotension, hyperglycemia, hypothermia, antinociception, and regulation of intestinal motility and secretion. [provided by RefSeq, Jul 2008]