Gene

NTSR1

Species
Homo sapiens
Symbol
NTSR1
Name
neurotensin receptor 1
Synonyms
  • high-affinity levocabastine-insensitive neurotensin receptor
  • neurotensin receptor 1 (high affinity)
Biotype
protein coding gene
Automated Description
Enables G protein-coupled neurotensin receptor activity and identical protein binding activity. Involved in negative regulation of apoptotic process and neuropeptide signaling pathway. Located in membrane raft and plasma membrane. Implicated in schizophrenia. Biomarker of Parkinson's disease.
RGD Description
Neurotensin receptor 1 belongs to the large superfamily of G-protein coupled receptors. NTSR1 mediates the multiple functions of neurotensin, such as hypotension, hyperglycemia, hypothermia, antinociception, and regulation of intestinal motility and secretion. [provided by RefSeq, Jul 2008]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24243
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCh38
Viewer Help
62.710M62.715M62.720M62.725M62.730M62.735M62.740M62.745M62.750M62.755M62.760M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions