Species | Gene symbol | Count | Best | Best reverse | Method Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN |
---|---|---|---|---|---|
Mus musculus | Pde8b | 10 of 10 | Yes | Yes | ☑☑☑☑☑☑☑☑☑☑ |
Rattus norvegicus | Pde8b | 10 of 10 | Yes | Yes | ☑☑☑☑☑☑☑☑☑☑ |
Xenopus tropicalis | pde8b | 4 of 9 | Yes | Yes | ☑ ☐☐☑☑☐☑☐☐ |
Danio rerio | pde8b | 10 of 10 | Yes | Yes | ☑ ☑☑☑☑☑☑☑☑ ☑ |
Drosophila melanogaster | Pde8 | 9 of 9 | Yes | Yes | ☑ ☑☑☑☑☑☑☑☑ |
Caenorhabditis elegans | pde-6 | 7 of 9 | Yes | Yes | ☑ ☐☑☐☑☑☑☑☑ |
Gene symbol | Rank | Alignment Length (aa) | Similarity % | Identity % | Method Count | Method Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD |
---|---|---|---|---|---|---|
PDE8A | 1 | 910 | 75 | 61 | 8 of 8 | ☑ ☑☑☑☑☑☑☑ |
PDE11A | 2 | 1018 | 35 | 21 | 3 of 8 | ☑ ☐☐☐☐☑☑☐ |
PDE10A | 3 | 1051 | 33 | 20 | 2 of 8 | ☐ ☐☐☐☐☑☑☐ |
PDE3B | 4 | 843 | 38 | 23 | 3 of 8 | ☑ ☐☐☐☐☑☑☐ |
PDE5A | 5 | 967 | 34 | 19 | 3 of 8 | ☑ ☐☐☐☐☑☑☐ |
PDE6B | 6 | 807 | 38 | 20 | 3 of 8 | ☑ ☐☐☐☐☑☑☐ |
PDE4B | 7 | 634 | 43 | 26 | 4 of 8 | ☑ ☐☐☑☐☑☑☐ |
PDE6A | 8 | 762 | 38 | 20 | 3 of 8 | ☑ ☐☐☐☐☑☑☐ |
PDE4A | 9 | 586 | 43 | 27 | 4 of 8 | ☑ ☐☐☑☐☑☑☐ |
PDE4D | 10 | 559 | 46 | 27 | 4 of 8 | ☑ ☐☐☑☐☑☑☐ |
PDE4C | 11 | 570 | 44 | 27 | 4 of 8 | ☑ ☐☐☑☐☑☑☐ |
PDE9A | 12 | 620 | 41 | 25 | 3 of 8 | ☑ ☐☐☐☐☑☑☐ |
PDE3A | 13 | 618 | 39 | 23 | 3 of 8 | ☑ ☐☐☐☐☑☑☐ |
PDE2A | 14 | 640 | 38 | 23 | 2 of 8 | ☑ ☐☐☐☐☐☑☐ |
PDE1C | 15 | 451 | 47 | 25 | 3 of 8 | ☑ ☐☐☐☐☑☑☐ |
PDE1A | 16 | 405 | 49 | 27 | 3 of 8 | ☑ ☐☐☐☐☑☑☐ |
PDE7A | 17 | 365 | 52 | 31 | 3 of 8 | ☑ ☐☐☐☐☑☑☐ |
PDE1B | 18 | 446 | 43 | 27 | 2 of 8 | ☐ ☐☐☐☐☑☑☐ |
PDE7B | 19 | 403 | 47 | 27 | 3 of 8 | ☑ ☐☐☐☐☑☑☐ |
PDE6C | 20 | 327 | 46 | 26 | 3 of 8 | ☑ ☐☐☐☐☑☑☐ |
Phenotype Term | Annotation details | References |
---|---|---|
Abnormality of movement | ||
Adrenal hyperplasia | ||
Autosomal dominant inheritance | ||
Bradykinesia | ||
Brisk reflexes | ||
Degeneration of the striatum | ||
Dysarthria | ||
Dysdiadochokinesis | ||
Dysphagia | ||
Gait disturbance |
PDE8B molecule type | Interactor gene | Interactor species | Interactor molecule type | Detection methods | Source | Reference |
---|---|---|---|---|---|---|
protein | FOXO1 | Homo sapiens | protein |
| PMID:36964488 | |
protein | PDE8A | Homo sapiens | protein |
| PMID:33961781 | |
protein | SNX27 | Homo sapiens | protein |
| PMID:34315543 | |
protein | UCHL1 | Homo sapiens | protein |
| PMID:32120844 | |
protein | XPO1 | Homo sapiens | protein |
| PMID:26673895 |