Gene

PEX13

Species
Homo sapiens
Symbol
PEX13
Name
peroxisomal biogenesis factor 13
Synonyms
  • NALD
  • PBD11A
Biotype
protein coding gene
Automated Description
Enables protein transmembrane transporter activity. Involved in cellular response to reactive oxygen species; protein import into peroxisome matrix, docking; and protein import into peroxisome matrix, translocation. Located in peroxisome. Is active in peroxisomal membrane. Implicated in Peroxisome biogenesis disorder 11B and peroxisome biogenesis disorder 11A.
RGD Description
This gene encodes a peroxisomal membrane protein that binds the type 1 peroxisomal targeting signal receptor via a SH3 domain located in the cytoplasm. Mutations and deficiencies in peroxisomal protein importing and peroxisome assembly lead to peroxisomal biogenesis disorders, an example of which is Zellweger syndrome. [provided by RefSeq, Oct 2008]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR19332
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Mus musculusPex1310 of 10YesYes  
Rattus norvegicusPex1310 of 10YesYes  
Xenopus laevispex13.L1 of 1YesYes           
Xenopus tropicalispex135 of 9YesYes   
Danio reriopex1310 of 10YesYes  
Drosophila melanogasterPex139 of 9YesYes   
Caenorhabditis elegansprx-139 of 9YesYes   
Saccharomyces cerevisiaePEX138 of 9YesYes   
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

No paralogs for the gene.

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
Phenotype Term
Annotation details
References
Abnormal chorioretinal morphology
Abnormal epiphysis morphology
Abnormal palate morphology
Abnormal pinna morphology
Abnormality of coagulation
Abnormality of metabolism/homeostasis
Abnormality of movement
Abnormality of neuronal migration
Abnormality of retinal pigmentation
Abnormality of the face
Showing 1 - 10 of 105 rows
per page

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Transgenic Alleles

No data available

Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
GRCh38
Viewer Help
61.020M61.025M61.030M61.035M61.040M61.045M61.050M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

34 interactor genes based on 57 annotations
PEX13 molecule type
Interactor gene
Interactor species
Interactor molecule type
Detection methods
Source
Reference
protein
ACBD5Homo sapiens
protein
  • proximity labelling technology
PMID:34079125
protein
ADAM10Homo sapiens
protein
  • phage display
PMID:25036101
protein
AGPSHomo sapiens
protein
  • proximity labelling technology
PMID:34079125
protein
AKAP1Homo sapiens
protein
  • proximity labelling technology
PMID:34079125
protein
ARHGEF39Homo sapiens
protein
  • affinity chromatography technology
PMID:33961781
protein
ATP5PFHomo sapiens
protein
  • affinity chromatography technology
PMID:33961781
protein
BTN3A2Homo sapiens
protein
  • affinity chromatography technology
PMID:26186194
protein
BTN3A2Homo sapiens
protein
  • affinity chromatography technology
PMID:28514442
protein
BTN3A2Homo sapiens
protein
  • affinity chromatography technology
PMID:33961781
protein
C3AR1Homo sapiens
protein
  • affinity chromatography technology
PMID:28514442
Showing 1 - 10 of 57 rows
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Genetic Interactions