Enables transmembrane signaling receptor activity. Involved in several processes, including homophilic cell adhesion via plasma membrane adhesion molecules; positive regulation of neuron projection development; and positive regulation of translation. Located in cell surface and extracellular exosome. Is active in plasma membrane.
RGD Description
Members of the B class of plexins, such as PLXNB2 are transmembrane receptors that participate in axon guidance and cell migration in response to semaphorins (Perrot et al. (2002) [PubMed 12183458]).[supplied by OMIM, Mar 2008]