Gene

POLL

Species
Homo sapiens
Symbol
POLL
Name
DNA polymerase lambda
Synonyms
  • BETAN
  • DNA polymerase beta-2
Biotype
protein coding gene
Automated Description
Enables 5'-deoxyribose-5-phosphate lyase activity and DNA-directed DNA polymerase activity. Involved in DNA metabolic process. Located in nucleoplasm. Is active in site of double-strand break.
RGD Description
This gene encodes a DNA polymerase. DNA polymerases catalyze DNA-template-directed extension of the 3'-end of a DNA strand. This particular polymerase, which is a member of the X family of DNA polymerases, likely plays a role in non-homologous end joining and other DNA repair processes. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2010]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11276
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Mus musculusPoll10 of 10YesYes  
Rattus norvegicusPoll10 of 10YesYes  
Xenopus laevispoll.L1 of 1YesYes           
Danio reriopoll10 of 10YesYes  
Saccharomyces cerevisiaePOL45 of 9YesYes   
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
POLM157840263 of 8  
DNTT261439223 of 8  
POLB338349325 of 8  

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Transgenic Alleles

No data available

Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
GRCh38
Viewer Help
101.579M101.580M101.581M101.582M101.583M101.584M101.585M101.586M101.587M101.588M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions