Gene

PPA1

Species
Homo sapiens
Symbol
PPA1
Name
inorganic pyrophosphatase 1
Synonyms
  • cytosolic inorganic pyrophosphatase
  • diphosphate phosphohydrolase
Biotype
protein coding gene
Automated Description
Predicted to enable inorganic diphosphate phosphatase activity. Predicted to be involved in phosphate-containing compound metabolic process. Located in extracellular exosome.
RGD Description
The protein encoded by this gene is a member of the inorganic pyrophosphatase (PPase) family. PPases catalyze the hydrolysis of pyrophosphate to inorganic phosphate, which is important for the phosphate metabolism of cells. Studies of a similar protein in bovine suggested a cytoplasmic localization of this enzyme. [provided by RefSeq, Jul 2008]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10286
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCh38
Viewer Help
70.205M70.210M70.215M70.220M70.225M70.230M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions