Predicted to enable several functions, including anion binding activity; calcium-dependent phospholipid binding activity; and metal ion binding activity. Involved in synaptic vesicle priming. Acts upstream of or within spontaneous neurotransmitter secretion. Predicted to be located in cytosol; dendritic spine; and secretory vesicle. Predicted to be extrinsic component of membrane. Predicted to be part of protein-containing complex. Predicted to be active in several cellular components, including cholinergic synapse; neuromuscular junction; and postsynaptic membrane. Predicted to be extrinsic component of synaptic vesicle membrane. Predicted to colocalize with Golgi apparatus. Is expressed in hindbrain; medulla oblongata; and midbrain. Orthologous to human RPH3A (rabphilin 3A).
MGI Description
PHENOTYPE: Homozygous mutants are viable and fertile and do not exhibit any obvious abnormal phenotypes. [provided by MGI curators]