Enables cytokine activity. Acts upstream of or within several processes, including negative regulation of meiotic nuclear division; positive regulation of peptidyl-tyrosine phosphorylation; and tyrosine phosphorylation of STAT protein. Predicted to be located in extracellular space. Is expressed in several structures, including aorta-gonad-mesonephros; future spinal cord; genitourinary system; submandibular gland; and trophectoderm. Orthologous to human OSM (oncostatin M).
MGI Description
PHENOTYPE: Homozygous mutant mice display decreased noxious responses in models of acute thermal, mechanical, chemical, and visceral pain. [provided by MGI curators]