Gene

Osm

Species
Mus musculus
Symbol
Osm
Name
oncostatin M
Synonyms
  • OncoM
Biotype
protein coding gene
Automated Description
Enables cytokine activity. Acts upstream of or within several processes, including negative regulation of meiotic nuclear division; positive regulation of peptidyl-tyrosine phosphorylation; and tyrosine phosphorylation of STAT protein. Predicted to be located in extracellular space. Is expressed in several structures, including aorta-gonad-mesonephros; future spinal cord; genitourinary system; submandibular gland; and trophectoderm. Orthologous to human OSM (oncostatin M).
MGI Description
PHENOTYPE: Homozygous mutant mice display decreased noxious responses in models of acute thermal, mechanical, chemical, and visceral pain. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR14261
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
4.1870M4.1875M4.1880M4.1885M4.1890M4.1895M4.1900M4.1905M4.1910M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions