Gene

Jrk

Species
Mus musculus
Symbol
Jrk
Name
jerky
Synonyms
None
Biotype
protein coding gene
Automated Description
Enables mRNA binding activity. Predicted to be involved in positive regulation of canonical Wnt signaling pathway. Located in cytoplasm and nucleus. Part of ribonucleoprotein complex. Is expressed in several structures, including central nervous system; early conceptus; eye; and genitourinary system. Orthologous to human JRK (Jrk helix-turn-helix protein).
MGI Description
PHENOTYPE: Heterozygous mutants show whole body jerks, clonic seizures and epileptic brain activity. Homozygous mutants show elevated seizure susceptibility, impaired postnatal growth, reduced life span, male sterility and impaired female fertility. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR19303
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
74.575M74.576M74.577M74.578M74.579M74.580M74.581M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions