DNA segment, Chr 18, Wayne State University 100, expressed
Biotype
protein coding gene
Automated Description
Enables alpha-tubulin binding activity and ubiquitin-protein transferase activity. Involved in regulation of cell cycle. Acts upstream of or within acrosome reaction. Located in acrosomal vesicle. Is expressed in extraembryonic component; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in anencephaly. Orthologous to human TRIM36 (tripartite motif containing 36).
MGI Description
PHENOTYPE: Male mice for a null allele exhibit normal fertility. [provided by MGI curators]