Predicted to enable voltage-gated monoatomic anion channel activity. Involved in sperm mitochondrial sheath assembly. Acts upstream of or within behavioral fear response; learning; and neuron-neuron synaptic transmission. Located in mitochondrion. Orthologous to human VDAC3 (voltage dependent anion channel 3).
MGI Description
PHENOTYPE: Homozygous null mutants are male sterile with reduced sperm motility and structural defects in the majority of axonemes in epididymal sperm. Mutants of both genders show deficits in behavioral tests measuring contextual or cued fear conditioning. [provided by MGI curators]