Gene

Gadd45b

Species
Mus musculus
Symbol
Gadd45b
Name
growth arrest and DNA-damage-inducible 45 beta
Synonyms
  • AI323528
  • expressed sequence AI323528
Biotype
protein coding gene
Automated Description
Acts upstream of or within negative regulation of protein kinase activity; positive regulation of MAPK cascade; and regulation of cell cycle. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including cardiovascular system; embryo mesenchyme; future brain; hindlimb long bone; and sensory organ. Orthologous to human GADD45B (growth arrest and DNA damage inducible beta).
MGI Description
PHENOTYPE: Homozygous inactivation of this locus affects immune response. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10411
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
80.7660M80.7662M80.7664M80.7666M80.7668M80.7670M80.7672M80.7674M80.7676M80.7678M80.7680M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions