Gene

Gng5

Species
Mus musculus
Symbol
Gng5
Name
G protein subunit gamma 5
Synonyms
  • G(y)5
  • Hg3l1
Biotype
protein coding gene
Automated Description
Predicted to enable G-protein beta-subunit binding activity and PDZ domain binding activity. Acts upstream of or within positive regulation of neural precursor cell proliferation and positive regulation of secondary heart field cardioblast proliferation. Located in mitochondrion. Is expressed in several structures, including central nervous system; early conceptus; oocyte; and retina. Orthologous to human GNG5 (G protein subunit gamma 5).
MGI Description
PHENOTYPE: Mice homozygous for a null allele exhibit abnormal headfolds, hypoplastic pharyngeal arches, severe cardiac defects including absence of formation of the right ventricle and outflow tract, and complete embryonic lethality. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR13809
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
146.206M146.207M146.208M146.209M146.210M146.211M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions