Predicted to enable G-protein beta-subunit binding activity and PDZ domain binding activity. Acts upstream of or within positive regulation of neural precursor cell proliferation and positive regulation of secondary heart field cardioblast proliferation. Located in mitochondrion. Is expressed in several structures, including central nervous system; early conceptus; oocyte; and retina. Orthologous to human GNG5 (G protein subunit gamma 5).
MGI Description
PHENOTYPE: Mice homozygous for a null allele exhibit abnormal headfolds, hypoplastic pharyngeal arches, severe cardiac defects including absence of formation of the right ventricle and outflow tract, and complete embryonic lethality. [provided by MGI curators]