Gene

Pkn2

Species
Mus musculus
Symbol
Pkn2
Name
protein kinase N2
Synonyms
  • 6030436C20Rik
  • AI507382
Biotype
protein coding gene
Automated Description
Predicted to enable RNA polymerase binding activity; histone deacetylase binding activity; and protein serine/threonine kinase activity. Involved in apical junction assembly. Located in apical junction complex; cytoplasm; and nucleus. Is expressed in several structures, including genitourinary system; heart; liver; lung; and spleen. Orthologous to human PKN2 (protein kinase N2).
MGI Description
PHENOTYPE: Mice homozygous for a null allele display embryonic lethality during organogenesis with impaired mesenchymal cell proliferation and neural crest cell migration. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24356
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
142.50M142.51M142.52M142.53M142.54M142.55M142.56M142.57M142.58M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions