Predicted to enable growth factor activity. Acts upstream of or within cell-matrix adhesion and extracellular matrix organization. Predicted to be located in extracellular region. Is expressed in several structures, including articular cartilage; autopod; respiratory system; sensory organ; and skeleton. Orthologous to human MIA (MIA SH3 domain containing).
MGI Description
PHENOTYPE: Mice homozygous for a targeted null mutation are viable and fertile but display alterations in the fibrillar ultrastructure of cartilage as well as minor changes in the number and morphology of chondrocytic microvilli. [provided by MGI curators]