Involved in dendrite development. Predicted to be located in cytosol and plasma membrane. Predicted to be active in membrane. Is expressed in ductus deferens; epididymis; ileum; prostate gland; and spleen. Human ortholog(s) of this gene implicated in graft-versus-host disease. Orthologous to human LST1 (leukocyte specific transcript 1).
MGI Description
PHENOTYPE: Mice homozygous for a knock-out allele are slightly more susceptible to influenza A H1N1 infection. [provided by MGI curators]