Version: 8.0.0
Date: Tue Jan 28 2025
Vamp7
Mus musculusMGI:1096399
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

Vamp7

Species
Mus musculus
Symbol
Vamp7
Name
vesicle-associated membrane protein 7
Synonyms
  • Sybl1
  • synaptobrevin like 1
Biotype
protein coding gene
Automated Description
Predicted to enable SNAP receptor activity and syntaxin binding activity. Involved in SNARE complex assembly and positive regulation of dendrite morphogenesis. Acts upstream of or within Golgi to plasma membrane protein transport and regulation of protein targeting to vacuolar membrane. Located in several cellular components, including cytoplasmic vesicle; lamellipodium; and pseudopodium. Is expressed in several structures, including adrenal gland; cerebral cortex; genitourinary system; liver; and spleen. Orthologous to human VAMP7 (vesicle associated membrane protein 7).
MGI Description
PHENOTYPE: Mice homozygous for a null mutation display an increased anxiety related response, increased circulating glycerol level, decreased body temperature, and decreased brain weight. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR21136

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    No data available

    Alleles and Variants

    Allele/Variant Symbol
    Allele Synonyms
    Category
    Variant
    Variant type
    Molecular consequence
    Has Disease Annotations
    Has Phenotype Annotations
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      Download all Alleles/Variants for all genes of the species

      Transgenic Alleles

      Species
      (carrying the transgene)
      Allele symbol
      Transgenic construct
      Expressed components
      Knock-down targets
      Regulatory regions
      Has Disease Annotations
      Has Phenotype Annotations
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        Models

        Model name
        Experimental condition
        Associated Human Diseases
        Associated Phenotypes
        Modifier
        Source
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          Sequence Feature Viewer

          No data available

          Sequence Details

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          Expression

          Primary Sources
          Other Sources
          Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

          Molecular Interactions

          Vamp7 molecule type
          Interactor gene
          Interactor species
          Interactor molecule type
          Detection methods
          Source
          Reference
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            Genetic Interactions

            Vamp7 role
            Vamp7 genetic perturbation
            Interactor gene
            Interactor species
            Interactor role
            Interactor genetic perturbation
            Interaction type
            Phenotype or trait
            Source
            Reference
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