Gene

Etv5

Species
Mus musculus
Symbol
Etv5
Name
ets variant 5
Synonyms
  • 1110005E01Rik
  • 8430401F14Rik
Biotype
protein coding gene
Automated Description
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including neuromuscular synaptic transmission; regulation of branching involved in mammary gland duct morphogenesis; and skeletal muscle acetylcholine-gated channel clustering. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; genitourinary system; and sensory organ. Used to study T-cell adult acute lymphocytic leukemia. Orthologous to human ETV5 (ETS variant transcription factor 5).
MGI Description
PHENOTYPE: Homozygous null mice display either male infertility, small testes, azoospermia, and failure to maintain spermatogonia or they are prenatally lethal. Preaxial polydactyly has also been observed. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11849
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
22.21M22.22M22.23M22.24M22.25M

Sequence Details

Loading...

Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions