Gene

Rbm4

Species
Mus musculus
Symbol
Rbm4
Name
RNA binding motif protein 4
Synonyms
  • Lark1
  • Rbm4a
Biotype
protein coding gene
Automated Description
Enables mRNA 3'-UTR binding activity and pre-mRNA binding activity. Involved in circadian regulation of translation; entrainment of circadian clock by photoperiod; and regulation of nucleocytoplasmic transport. Acts upstream of or within several processes, including insulin secretion involved in cellular response to glucose stimulus; regulation of gene expression; and regulation of insulin receptor signaling pathway. Located in nucleolus and perinuclear region of cytoplasm. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human RBM4 (RNA binding motif protein 4).
MGI Description
PHENOTYPE: Mice homozygous for a null mutation display reduced postnatal body weight, decreased insulin levels, smaller pancreatic islets and impaired glucose tolerance. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR23147
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
4.835M4.836M4.837M4.838M4.839M4.840M4.841M4.842M4.843M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions