Gene

Sema6b

Species
Mus musculus
Symbol
Sema6b
Name
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
Synonyms
  • Sema
  • Seman
Biotype
protein coding gene
Automated Description
Enables semaphorin receptor binding activity. Involved in axon guidance and hippocampus development. Predicted to be active in plasma membrane. Is expressed in several structures, including genitourinary system; liver; musculature; spinal cord; and spleen. Human ortholog(s) of this gene implicated in progressive myoclonus epilepsy. Orthologous to human SEMA6B (semaphorin 6B).
MGI Description
PHENOTYPE: Mice homozygous for a knock-out allele exhibit abnormal mossy fiber and mossy cell axon projections, thickened suprapyramidal bundles, and elongated infrapyramydal bundles. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11036
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
56.432M56.434M56.436M56.438M56.440M56.442M56.444M56.446M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions