Gene

Cacybp

Species
Mus musculus
Symbol
Cacybp
Name
calcyclin binding protein
Synonyms
None
Biotype
protein coding gene
Automated Description
Enables molecular adaptor activity; protein domain specific binding activity; and ubiquitin protein ligase binding activity. Acts upstream of or within cellular response to leukemia inhibitory factor. Located in cytoplasm and nuclear envelope lumen. Part of SCF ubiquitin ligase complex. Is expressed in several structures, including alimentary system; genitourinary system; liver lobe; nervous system; and sensory organ. Orthologous to human CACYBP (calcyclin binding protein).
MGI Description
PHENOTYPE: Mice homozygous for a null allele exhibit reduced thymus and spleen cellularity, and defects in TCR-rearrangement. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR13164
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
160.030M160.031M160.032M160.033M160.034M160.035M160.036M160.037M160.038M160.039M160.040M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions